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MAPT

—Microtubule Associated Protein Tau

Chromosome: 17

Location: 17:45894278-46028334

OMIM: 157140

Ensembl: ENSG00000186868

Official·OMIM:157140 Official·ENSG00000186868

Encodes tau protein. Mutations cause frontotemporal dementia and parkinsonism.

Treatment Roadmap — MAPT

Preclinical

Phase 1

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Frontotemporal Dementia

Autosomal DominantPrevalence: 1/10000neurological

Official·OMIM:600274 Official·ORPHA282

Summary

Clinical Trial

Approved Therapy

Registered Variant