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MFN2

—Mitofusin 2

Chromosome: 1

Location: 1:11980181-12015211

OMIM: 608507

Ensembl: ENSG00000116688

Official·OMIM:608507 Official·ENSG00000116688

Encodes mitochondrial fusion protein. Mutations cause CMT2A.

Treatment Roadmap — MFN2

Preclinical

Phase 1

1 trial

Phase 2

1 trial

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Charcot-Marie-Tooth Disease Type 2A

Autosomal DominantPrevalence: 1/20000neurological

Official·OMIM:609260 Official·ORPHA99946

Summary

Clinical Trial

Approved Therapy

Registered Variant