The information on this page is for informational purposes only and does not constitute medical advice. Consult your genetic counselor or specialist physician for treatment decisions.

MSH2

—MutS Homolog 2

Chromosome: 2

Location: 2:47403067-47663146

OMIM: 609309

Ensembl: ENSG00000095002

Official·OMIM:609309 Official·ENSG00000095002

Encodes DNA mismatch repair protein. Mutations cause Lynch syndrome.

Treatment Roadmap — MSH2

Preclinical

Phase 1

Phase 2

5 trial

Phase 3

2 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Lynch Syndrome

Autosomal DominantPrevalence: 1/440oncologic

Official·OMIM:120435 Official·ORPHA144

Summary

Clinical Trial

Approved Therapy

Registered Variant