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MSH6

—MutS Homolog 6

Chromosome: 2

Location: 2:47695530-47810109

OMIM: 600678

Ensembl: ENSG00000116062

Official·OMIM:600678 Official·ENSG00000116062

Encodes DNA mismatch repair protein. Associated with Lynch syndrome.

Treatment Roadmap — MSH6

Preclinical

Phase 1

1 trial

Phase 2

3 trial

Phase 3

2 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Lynch Syndrome

Autosomal DominantPrevalence: 1/440oncologic

Official·OMIM:120435 Official·ORPHA144

Summary

Clinical Trial

Approved Therapy

Registered Variant