The information on this page is for informational purposes only and does not constitute medical advice. Consult your genetic counselor or specialist physician for treatment decisions.

NAGLU

—N-Acetyl-Alpha-Glucosaminidase

Chromosome: 17

Location: 17:42536216-42544449

OMIM: 609701

Ensembl: ENSG00000108784

Official·OMIM:609701 Official·ENSG00000108784

Encodes alpha-N-acetylglucosaminidase enzyme. Mutations cause MPS IIIB (Sanfilippo B).

Treatment Roadmap — NAGLU

Preclinical

Phase 1

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Sanfilippo Syndrome Type B

Autosomal RecessivePrevalence: 1/200000lysosomal

Official·OMIM:252920 Official·ORPHA581

Summary

Clinical Trial

Approved Therapy

Registered Variant