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NDUFS1

—NADH:Ubiquinone Oxidoreductase Core Subunit S1

Chromosome: 2

Location: 2:206114817-206159524

OMIM: 157655

Ensembl: ENSG00000023228

Official·OMIM:157655 Official·ENSG00000023228

Encodes complex I subunit. Mutations cause mitochondrial complex I deficiency.

Treatment Roadmap — NDUFS1

Preclinical

Phase 1

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Mitochondrial Complex I Deficiency

Autosomal RecessivePrevalence: 1/100000mitochondrial

Official·OMIM:252010 Official·ORPHA2609

Summary

Clinical Trial

Approved Therapy

Registered Variant