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NF1

—Neurofibromin 1

Chromosome: 17

Location: 17:31094883-31382116

OMIM: 613113

Ensembl: ENSG00000196712

Official·OMIM:613113 Official·ENSG00000196712

Encodes tumor suppressor neurofibromin. Mutations cause NF1.

Treatment Roadmap — NF1

Preclinical

Phase 1

5 trial

Phase 2

12 trial

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Neurofibromatosis Type 1

Autosomal DominantPrevalence: ~1/3000neurological

Official·OMIM:162200 Official·ORPHA636

Summary

Clinical Trial

Approved Therapy

Registered Variant