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NF2

—Neurofibromin 2

Chromosome: 22

Location: 22:29603520-29698598

OMIM: 607379

Ensembl: ENSG00000186575

Official·OMIM:607379 Official·ENSG00000186575

Encodes merlin tumor suppressor protein. Mutations cause NF2 and schwannomatosis.

Treatment Roadmap — NF2

Preclinical

Phase 1

2 trial

Phase 2

3 trial

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Neurofibromatosis Type 2

Autosomal DominantPrevalence: 1/60000oncologic

Official·OMIM:101000 Official·ORPHA637

Summary

Clinical Trial

Approved Therapy

Registered Variant