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PALB2

—Partner And Localizer Of BRCA2

Chromosome: 16

Location: 16:23603158-23641342

OMIM: 610355

Ensembl: ENSG00000083093

Official·OMIM:610355 Official·ENSG00000083093

Encodes protein interacting with BRCA2. Mutations predispose to breast cancer.

Treatment Roadmap — PALB2

Preclinical

Phase 1

7 trial

Phase 2

21 trial

Phase 3

3 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Hereditary Breast-Ovarian Cancer Syndrome

Autosomal DominantPrevalence: 1/500oncologic

Official·OMIM:604370 Official·ORPHA145

Summary

Clinical Trial

Approved Therapy

Registered Variant