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PINK1

—PTEN Induced Kinase 1

Chromosome: 1

Location: 1:20633436-20652231

OMIM: 608309

Ensembl: ENSG00000158828

Official·OMIM:608309 Official·ENSG00000158828

Encodes mitochondrial serine/threonine kinase. Mutations cause PARK6 Parkinson disease.

Treatment Roadmap — PINK1

Preclinical

Phase 1

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Early-Onset Parkinson Disease

Autosomal RecessivePrevalence: 1/10000neurological

Official·OMIM:600116 Official·ORPHA2828

Summary

Clinical Trial

Approved Therapy

Registered Variant