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PMS2

—PMS1 Homolog 2

Chromosome: 7

Location: 7:5970925-6009130

OMIM: 600259

Ensembl: ENSG00000122512

Official·OMIM:600259 Official·ENSG00000122512

Encodes DNA mismatch repair protein. Associated with Lynch syndrome type 4.

Treatment Roadmap — PMS2

Preclinical

Phase 1

1 trial

Phase 2

3 trial

Phase 3

1 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Lynch Syndrome

Autosomal DominantPrevalence: 1/440oncologic

Official·OMIM:120435 Official·ORPHA144

Summary

Clinical Trial

Approved Therapy

Registered Variant