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PSEN2

—Presenilin 2

Chromosome: 1

Location: 1:226870184-226927726

OMIM: 600759

Ensembl: ENSG00000143801

Official·OMIM:600759 Official·ENSG00000143801

Encodes presenilin 2 protein. Mutations cause familial Alzheimer disease.

Treatment Roadmap — PSEN2

Preclinical

Phase 1

Phase 2

1 trial

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Early-Onset Alzheimer Disease

Autosomal DominantPrevalence: 1/10000neurological

Official·OMIM:104300 Official·ORPHA1020

Summary

Clinical Trial

Approved Therapy

Registered Variant