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PTCH1

—Patched 1

Chromosome: 9

Location: 9:95442980-95517057

OMIM: 601309

Ensembl: ENSG00000185920

Official·OMIM:601309 Official·ENSG00000185920

Encodes Hedgehog signaling pathway receptor. Mutations cause Gorlin syndrome.

Treatment Roadmap — PTCH1

Preclinical

Phase 1

Phase 2

4 trial

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Gorlin Syndrome

Autosomal DominantPrevalence: 1/60000oncologic

Official·OMIM:109400 Official·ORPHA377

Summary

Clinical Trial

Approved Therapy

Registered Variant