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PTEN

—Phosphatase And Tensin Homolog

Chromosome: 10

Location: 10:87862638-87971930

OMIM: 601728

Ensembl: ENSG00000171862

Official·OMIM:601728 Official·ENSG00000171862

Encodes phosphatase tumor suppressor. Mutations cause Cowden syndrome.

Treatment Roadmap — PTEN

Preclinical

Phase 1

12 trial

Phase 2

43 trial

Phase 3

4 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Cowden Syndrome

Autosomal DominantPrevalence: 1/200000oncologic

Official·OMIM:158350 Official·ORPHA201

Summary

Clinical Trial

Approved Therapy

Registered Variant