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RAG1

—Recombination Activating 1

Chromosome: 11

Location: 11:36510348-36593156

OMIM: 179615

Ensembl: ENSG00000166349

Official·OMIM:179615 Official·ENSG00000166349

Encodes V(D)J recombinase enzyme. Mutations cause Omenn syndrome and SCID.

Treatment Roadmap — RAG1

Preclinical

Phase 1

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Omenn Syndrome

Autosomal RecessivePrevalence: 1/500000immunologic

Official·OMIM:603554 Official·ORPHA39041

Summary

Clinical Trial

Approved Therapy

Registered Variant