The information on this page is for informational purposes only and does not constitute medical advice. Consult your genetic counselor or specialist physician for treatment decisions.

RUNX2

—RUNX Family Transcription Factor 2

Chromosome: 6

Location: 6:45328157-45664349

OMIM: 600211

Ensembl: ENSG00000124813

Official·OMIM:600211 Official·ENSG00000124813

Encodes bone development transcription factor. Mutations cause cleidocranial dysplasia.

Treatment Roadmap — RUNX2

Preclinical

Phase 1

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Cleidocranial Dysplasia

Autosomal DominantPrevalence: 1/1000000skeletal

Official·OMIM:119600 Official·ORPHA1452

Summary

Clinical Trial

Approved Therapy

Registered Variant