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SCN1A

—Sodium Voltage-Gated Channel Alpha Subunit 1

Chromosome: 2

Location: 2:165984641-166182806

OMIM: 182389

Ensembl: ENSG00000144285

Official·OMIM:182389 Official·ENSG00000144285

Encodes voltage-gated sodium channel alpha subunit. Mutations cause Dravet syndrome.

Treatment Roadmap — SCN1A

Preclinical

Phase 1

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Dravet Syndrome

Autosomal DominantPrevalence: 1/20000neurological

Official·OMIM:607208 Official·ORPHA33069

Summary

Clinical Trial

Approved Therapy

Registered Variant