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SLC12A3

—Solute Carrier Family 12 Member 3

Chromosome: 16

Location: 16:56865203-56915850

OMIM: 600968

Ensembl: ENSG00000070915

Official·OMIM:600968 Official·ENSG00000070915

Encodes NCC thiazide-sensitive sodium-chloride co-transporter. Mutations cause Gitelman syndrome.

Treatment Roadmap — SLC12A3

Preclinical

Phase 1

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Gitelman Syndrome

Autosomal RecessivePrevalence: 1/40000renal

Official·OMIM:263800 Official·ORPHA358

Summary

Clinical Trial

Approved Therapy

Registered Variant