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SNCA

—Synuclein Alpha

Chromosome: 4

Location: 4:89700345-89838321

OMIM: 163890

Ensembl: ENSG00000145335

Official·OMIM:163890 Official·ENSG00000145335

Encodes alpha-synuclein. Mutations and duplications cause familial Parkinson disease.

Treatment Roadmap — SNCA

Preclinical

Phase 1

Phase 2

1 trial

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Early-Onset Parkinson Disease

Autosomal DominantPrevalence: 1/10000neurological

Official·OMIM:600116 Official·ORPHA2828

Summary

Clinical Trial

Approved Therapy

Registered Variant