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STAT3

—Signal Transducer And Activator Of Transcription 3

Chromosome: 17

Location: 17:42313324-42388568

OMIM: 102582

Ensembl: ENSG00000168610

Official·OMIM:102582 Official·ENSG00000168610

Encodes signal transducer and transcription activator. Mutations cause Hyper-IgE syndrome.

Treatment Roadmap — STAT3

Preclinical

Phase 1

5 trial

Phase 2

5 trial

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Hyper-IgE Syndrome

Autosomal DominantPrevalence: 1/1000000immunologic

Official·OMIM:147060 Official·ORPHA2314

Summary

Clinical Trial

Approved Therapy

Registered Variant