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TGM1

—Transglutaminase 1

Chromosome: 14

Location: 14:24249114-24264432

OMIM: 190195

Ensembl: ENSG00000092295

Official·OMIM:190195 Official·ENSG00000092295

Encodes transglutaminase 1 enzyme. Mutations cause lamellar ichthyosis.

Treatment Roadmap — TGM1

Preclinical

Phase 1

Phase 2

Phase 3

1 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Lamellar Ichthyosis

Autosomal RecessivePrevalence: 1/200000dermatologic

Official·OMIM:242300 Official·ORPHA313

Summary

Clinical Trial

Approved Therapy

Registered Variant