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TP53

—Tumor Protein P53

Chromosome: 17

Location: 17:7661779-7687546

OMIM: 191170

Ensembl: ENSG00000141510

Official·OMIM:191170 Official·ENSG00000141510

Encodes tumor suppressor p53 protein. The most commonly mutated gene in cancer.

Treatment Roadmap — TP53

Preclinical

Phase 1

26 trial

Phase 2

26 trial

Phase 3

9 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Li-Fraumeni Syndrome

Autosomal DominantPrevalence: 1/5000oncologic

Official·OMIM:151623 Official·ORPHA524

Summary

112

Clinical Trial

Approved Therapy

Registered Variant