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TPP1

—Tripeptidyl Peptidase 1

Chromosome: 11

Location: 11:6612768-6619448

OMIM: 607998

Ensembl: ENSG00000166340

Official·OMIM:607998 Official·ENSG00000166340

Encodes tripeptidyl peptidase 1 enzyme. Mutations cause CLN2 (Batten) disease.

Treatment Roadmap — TPP1

Preclinical

Phase 1

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Neuronal Ceroid Lipofuscinosis Type 2

Autosomal RecessivePrevalence: 1/200000lysosomal

Official·OMIM:204500 Official·ORPHA228349

Summary

Clinical Trial

Approved Therapy

Registered Variant