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TTN

—Titin

Chromosome: 2

Location: 2:178525989-178830802

OMIM: 188840

Ensembl: ENSG00000155657

Official·OMIM:188840 Official·ENSG00000155657

Encodes the largest human protein. Mutations are the most common genetic cause of dilated cardiomyopathy.

Treatment Roadmap — TTN

Preclinical

Phase 1

Phase 2

1 trial

Phase 3

3 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Dilated Cardiomyopathy (TTN-related)

Autosomal DominantPrevalence: 1/2500cardiac

Official·OMIM:604145 Official·ORPHA217604

Summary

Clinical Trial

Approved Therapy

Registered Variant