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WT1

—WT1 Transcription Factor

Chromosome: 11

Location: 11:32387775-32435564

OMIM: 607102

Ensembl: ENSG00000184937

Official·OMIM:607102 Official·ENSG00000184937

Encodes transcription factor. Mutations cause Wilms tumor.

Treatment Roadmap — WT1

Preclinical

Phase 1

14 trial

Phase 2

15 trial

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Wilms Tumor

Autosomal DominantPrevalence: 1/10000oncologic

Official·OMIM:194070 Official·ORPHA654

Summary

Clinical Trial

Approved Therapy

Registered Variant