Molecular Genetics of Retinal Degenerations

Plain-language summary

This study investigates the molecular genetic causes of retinal degenerations (deterioration of the eye's light-sensing cells). It included individuals over age 4 with congenital, childhood, or age-related retinal degeneration and their family members. It is an observational (non-phase) study and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Completed

Sponsor

National Eye Institute (NEI)

Start date

9/26/2005

Estimated completion

6/23/2016

Countries

United States, China, India, Pakistan

Related genes

Locations

• Bethesda, United States
• Boston, United States
• Cleveland, United States
• Guangzhou, China
• Maduri, India
• Lahore, Pakistan

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

* INCLUSION CRITERIA:

Patients that meet diagnostic criteria for specific retinal degenerations will be recruited from the NEI and collaborating clinics.

Subjects with the following will be recruited:

1. Individuals or family members of individuals with Retinal degenerations, either congenital, childhood, or age related.
2. Adults must be capable of providing their own consent.
3. All subjects must be able to cooperate with study examination and phlebotomy.
4. Older than 4 years of age.

EXCLUSION CRITERIA:

1. Diseases, infections, or trauma that mimic primary retinal degenerations.
2. Children requiring sedation for study procedures.