International Pediatric Adrenocortical Tumor Registry

Plain-language summary

This is an international registry study that follows children diagnosed with an adrenocortical tumor. It is open to people aged 21 or younger with a suspected or confirmed tumor, their relatives who carry a TP53 mutation and have a cancer diagnosis, and their biological parents. Run by St. Jude Children's Research Hospital, it is a study without an assigned phase and is currently enrolling participants.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Recruiting

Sponsor

St. Jude Children's Research Hospital

Start date

10/1/2001

Estimated completion

12/1/2040

Countries

United States

Related genes

Locations

• Stanford, United States
• St. Petersburg, United States
• Dayton, United States
• Memphis, United States
• Fort Worth, United States

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

STRATIFICATION ASSIGNMENT:

* Stratum A: participant suspected or confirmed diagnosis of adrenocortical tumor (ACT)
* Stratum R: relative of participant with ACT and TP53 mutation who has diagnosis of malignancy
* Stratum P: biological parent of participant with ACT

Inclusion Criteria - Stratum A (participant with ACT):

* Age ≤ 21 years old at diagnosis
* Suspected or confirmed diagnosis of adrenocortical tumor (adenoma, carcinoma or undefined histology).
* Signed informed consent

Inclusion Criteria - Stratum R (relative):

* Any age
* Diagnosis of malignant tumor
* Signed informed consent

Inclusion Criteria - Stratum P (parent):

* Biological parent of Stratum A participant