Lp(a) and Aortic Valve Calcification

Plain-language summary

This observational study examines the relationship between Lp(a) levels and aortic valve calcification. It included men and women aged 18-80 with heterozygous familial hypercholesterolemia who carry a documented mutation in the LDL receptor gene. This was a study with no assigned phase and it has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Completed

Sponsor

Laval University

Start date

4/30/2017

Estimated completion

2/19/2020

Countries

Canada

Related genes

Locations

• Québec, Canada

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Men or women with heterozygous FH aged between 18 and 80 years
* FH patient carrying a documented mutation in the LDL receptor gene
* Subjects must be willing to give written informed consent and able to adhere to visit schedule

Exclusion Criteria:

* Men or women \< 18 or \> 80 years
* Non-FH subjects
* History of alcohol or drug abuse within the past 2 years
* Subjects who are in a situation or have any condition that, in the opinion of the investigator, may interfere with optimal participation in the study