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This observational study examined levels of the hormones ghrelin and obestatin in children with chronic kidney disease. It enrolled children who had been on hemodialysis for at least 3 months or had received a kidney transplant at least 6 months earlier, excluding those on growth hormone treatment. It was conducted as a study without an assigned phase and has been completed.
The summary above is a plain-language rendering of the official record. The original English title is shown for reference.
Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.
Inclusion Criteria: * the CKD-HD patients should have been on hemodialysis treatment for at least 3 months * the RTx patients should have received renal transplantation at least 6 months before Exclusion Criteria: * treatment with growth hormone * the presence of neurologic disability or syndromic diseases affecting per se food intake * for controls: they should have no history of chronic diseases and should not receive any medication. They should be on unrestricted diet.