Xylitol and Sorbitol Effects on the Oral Microbiome

Plain-language summary

This study evaluates the effects of xylitol- and sorbitol-containing chewing gum on the oral microbiome. Participants aged 18 and over with at least 20 teeth and no systemic, infectious or inflammatory disease are included. It is a study without an assigned phase and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Not Applicable

Status

Completed

Sponsor

The University of The West Indies

Intervention

Xylitol then Sorbitol gum, Sorbitol then Xylitol gum

Start date

3/5/2015

Estimated completion

6/4/2015

Related genes

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

To be eligible, subjects must have been 18 years and over, have had at least 20 teeth, provided written informed consent and been willing to comply with study procedures

Exclusion Criteria:

Subjects with systemic, infectious or inflammatory diseases or taking medicines, antibiotics or fluoride in the last month, habitual consumers of xylitol / sorbitol-containing products and mouth rinses, with abnormal salivary flow (\<1ml / min), pregnant, on contraceptive pills, or with abnormal dietary habits were excluded