Yükleniyor... / Loading...
This study examines the effects of compounds called polyphenols in olive oil on cardiovascular health biomarkers, comparing high- and low-polyphenol olive oils. It enrolled generally healthy men and women aged 20 to 45. The study is a non-phased study and is currently not recruiting but is still ongoing (active, not recruiting).
The summary above is a plain-language rendering of the official record. The original English title is shown for reference.
Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.
Inclusion Criteria: * Generally healthy male and female subjects within the range of 20-45 years of age and BMI range of 18.5-29.9 kg/m2 for the healthy weight/overweight group and ≥ 30 kg/m2 for the obese group will be recruited. Exclusion Criteria: * Adults unable to consent, individuals who are not yet adults (infants, children, teenagers), pregnant or lactating women, women planning to become pregnant in the next two months and prisoners will be specifically excluded * Documented chronic diseases including diabetes, thyroid disease, kidney disease, metabolic syndrome, active cancer, previous cardiovascular events, history of gastric bypass or other GI issues related to fat absorption * History of dyslipidemia or abnormal blood glucose levels (total cholesterol \>240 mg/dL, elevated fasting blood glucose levels \>125 mg/dL) * Allergy to olives, inability to tolerate gluten or multiple allergies/intolerances that would significantly limit food intake * Smoker or living with a smoker, illicit drug use, consuming \>1 alcoholic drink/day, vaporizer and/or electronic cigarette use * Extreme dietary or exercise patterns * Recent weight fluctuations (\>10% in the last 6 months) * Taking prescription lipid medications or supplements that may affect lipoprotein metabolism, \>1 g of fish oil/day, antioxidant supplements, cannabidiol (CBD) oil * Taking exogenous hormones (e.g. hormonal birth control) * Poor venous access * Unwillingness to comply with study protocol