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This study analyzes the bacterial microbiome in root-canal-infected primary and permanent teeth by collecting samples. It enrolled patients with intact roots and clinical crowns suitable for effective isolation, without certain signs of infection. It was a study without an assigned phase and has been completed.
The summary above is a plain-language rendering of the official record. The original English title is shown for reference.
Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.
Inclusion Criteria: * have intact roots or \<1/3 of physiological root resorption * have clinical crowns that permit effective rubber dam isolation * no mobility, fistula, pus discharge, gingival swelling, periapical abscess or internal resorption. Exclusion Criteria: * have marginal periodontitis, a history of pharmacological treatment, antibiotics or fluoride intake within the last 2 months * a history of cancer, diabetes or immunodeficiency disorders