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This study evaluated the effect of resistance exercise (strength training) in preventing bed-rest induced muscle loss in older adults. Men aged 65-80 in generally good health who had not done structured strength training in the past 10 years were eligible. It was a non-phase interventional study and has been completed.
The summary above is a plain-language rendering of the official record. The original English title is shown for reference.
Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.
Inclusion Criteria: * Males aged between 65-80 years * No history of structured resistance training within 10 years prior to study participation. * Generally good health as indicated by a thorough health questionnaire. * A score of ≥9 points on the Short Physical Performance Battery to assess lower extremity function. * Body Mass Index \<30kg/m2 Exclusion Criteria: * Coagulation disorders * Myocardial infarction * Artery/vein disease * Hormone replacement therapy * Other chronic/systemic illnesses (i.e. renal failure, chronic obstructive pulmonary disease, cancer). * Undergone 2 or more muscle biopsies from each leg previously. * Received a stable isotope infusion in the last 3 years prior to study enrollment.