Immunometabolic Effects of Non-drug Strategies in the Clinical Management of Obesity: Translational Study

Plain-language summary

This study examined the immunometabolic effects of non-drug strategies in the clinical management of obesity, comparing alpha lipoic acid plus full hospitalization with a placebo diet-and-exercise program. People aged 18-75 with a body mass index over 30 were eligible. It was a non-phase interventional study and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Not Applicable

Status

Completed

Sponsor

Fauqué

Intervention

Alpha lipoic acid (plus full hospitalization), Placebo (full hospitalization: dietary monitoring with an adapted physical activity program)

Start date

7/2/2018

Estimated completion

3/16/2020

Countries

France

Related genes

Locations

• Cannes, France

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* BMI\> 30; aged between 18 and 75 years

Exclusion Criteria:

* Pregnant and/or lactating women; not affiliated with social security; not mutual health insurance; person deprived of liberty; participation in clinical research in the last 6 months

Non-inclusion criteria:

* HLA-DRB1\*04-03/06 polymorphisms; recent hospitalization (\<1 month); food supplement based on antioxidant; medicated in fibrate/telmisartan (modulator of PPARs)