Genetic Testing and Motivational Counseling for FH

Plain-language summary

This study examines the effects of genetic testing and motivational counseling in people with familial hypercholesterolemia (FH), together with lipid analysis and cardiologist-lipidologist consultations. It enrolled people with a probable or definite FH diagnosis (6 points or more) according to the Dutch criteria. The study is a non-phase study; it is not currently recruiting but is ongoing (active, not recruiting).

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Not Applicable

Status

Active, not recruiting

Sponsor

National Medical Research Center for Therapy and Preventive Medicine

Intervention

Genetic Testing, Motivational Counseling, Lipid analysis, Consultation with a cardiologist-lipidologist (correction of therapy, lifestyle, diet), Visit 1, Visit 2, Visit 3, Visit 4

Start date

6/15/2020

Estimated completion

3/30/2025

Countries

Russia

Related genes

Locations

• Moscow, Russia

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Probable or definite diagnosis of FH according to the Dutch criteria (6 points or more);
* Signed informed consent;

Exclusion Criteria:

* Pregnancy or lactation at the time of enrollment
* Established active severe infectious disease or severe hematologic, metabolic, gastrointestinal or endocrine dysfunctions (for example, uncontrolled thyroid dysfunction or uncontrolled diabetes mellitus) in the opinion of the investigator
* Active liver disease
* Estimated GFR≤ 30 ml / min / 1.73m2
* Any other conditions at Visit 1 that, according to the investigator's opinion, render the patient ineligible for inclusion in the study, may interfere with the patient's participation in the study or patient's completion of the study.