Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part III

Plain-language summary

This study examines the early healing of oral soft tissues, both clinically and at the biomolecular level, in patients undergoing periodontal surgery, and evaluates the application of hyaluronic acid (HA). It enrolled non-smoking patients aged 30-60 in good general health who required periodontal surgery. It was a non-phased study and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Not Applicable

Status

Completed

Sponsor

University of Roma La Sapienza

Intervention

periodontal surgery + 24 hr buccal attached gingiva (G) biopsy, HA application

Start date

4/29/2021

Estimated completion

7/6/2021

Countries

Italy

Related genes

Locations

• Roma, Italy

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* patients that required periodontal surgery;
* patients age between 30-60 years;
* patients with full mouth plaque score and full mouth bleeding score \< 15%;
* patients with a good general healthy status;
* patients without any medicaments or drug consumption that can affect the healing process;
* non-smoking patients.

Exclusion Criteria:

* patients in pregnancy;
* patients in lactation period;
* patients with consumption of antibiotics or anti-inflammatory drugs in the previous six months;
* patients with systemic diseases.