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This study examined how cigarette smoking affects the outcome of gum (periodontal) treatment. It enrolled healthy people aged 35-75 with chronic periodontitis, both smokers and non-smokers, who received non-surgical gum treatment. This study has no assigned phase and has been completed.
The summary above is a plain-language rendering of the official record. The original English title is shown for reference.
Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.
Inclusion Criteria: * healthy subjects * age 35-75 years * diagnosed with chronic periodontitis * at least four non-adjacent teeth with proximal sites with a PD ≥6 mm and clinical attachment loss ≥5 mm with BoP and no radiographic signs of apical pathology. * either smokers (\>10 cigarettes per day for at least 5 years) or non-smokers (never smoked or not within the last 5 years). Exclusion Criteria: * subjects who presented with any current medical condition or used medications known to affect periodontal healing * incorrectly reported smoking status * use of antibiotics within 6 months of the study * received subgingival scaling within 6 months of the study