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This study examined the vitamin D receptor in the lining of the uterus (endometrium) in women with polycystic ovary syndrome (PCOS), with samples taken by the pipelle method. It enrolled women with a diagnosis of PCOS who were undergoing IVF/ICSI treatment. It was a study without an assigned phase and has been completed.
The summary above is a plain-language rendering of the official record. The original English title is shown for reference.
Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.
Inclusion Criteria: * Clinical diagnosis of PCOS * Approval for IVF/ICSI and total embryo freezing * Consent to endometrial sampling Exclusion Criteria: * Women with hyperandrogenism or ovulatory dysfunction due to non-PCOS etiologies. * Patients taking vitamin D, insulin sensitizers, lipid-lowering or other hormonal drugs in the last three months were not included. * Those with a history of mechanical endometrial injury, polypectomy, hysteroscopic myomectomy, endometrioma resection, dilatation/curettage, ovarian drilling and salpingectomy were also excluded. * Participants with premalignant or malignant endometrial pathology, those with a history of tubal factor infertility, congenital uterine anomaly or any chronic systemic diseases were not included. * Azoospermia patients were excluded from the study because we preferred ejaculate sperm for ICSI in patients in the control group.