Evaluation of Autonomic, Imaging and Genetic Markers for Parkinson-related Dementia : Longitudinal Assessment of a PD Cohort.

Plain-language summary

This study evaluates the value of autonomic, imaging and genetic markers, followed over time, in predicting the development of Parkinson-related dementia in a group of Parkinson's disease patients. Patients with clinically established Parkinson's disease and onset age between 40 and 70 were included. The study was conducted as a non-phase observational study and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Completed

Sponsor

IRCCS San Raffaele

Intervention

diagnostic accuracy

Start date

9/1/2018

Estimated completion

9/1/2020

Countries

Italy

Related genes

Locations

• Milan, Italy

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Diagnosis of "clinically established PD" based on the MDS clinical diagnostic criteria.

Age at disease onset will be between 40 and 70.

Exclusion Criteria:

* severe autonomic dysfunction (as defined in red flag 5a and 5b) will be an exclusion criterion Previous deep brain stimulation is an exclusion criterion.