Effect of Non-chirurgical Periodontal Treatment on the Immune System From a Gender Perspective

Plain-language summary

This study examined the effect of non-surgical periodontal treatment on the immune system from a gender perspective in people with gum disease (periodontitis) and obesity. It enrolled men and women with periodontitis and a body mass index of 30 kg/m2 or higher. The study did not use a phase designation and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Completed

Sponsor

Milagros Rocha Barajas

Intervention

non-chirurgical periodontal treatment

Start date

4/15/2024

Estimated completion

5/31/2025

Countries

Spain

Related genes

Locations

• Valencia, Spain
• Valencia, Spain

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

1. Men/Women with periodontitis:

   * Periodontitis will be diagnosed according to the definition of the Centers for Disease Control and Prevention / American Academy of Periodontology (CDC/AAP).
2. Men/Women with obesity:

   * Body mass index (BMI) ≥30 kg/m2 (WHO 2000)

Exclusion Criteria:

* Having fewer than fourteen teeth,
* Having infectious diseases
* Having other oral inflammatory diseases,
* Having received periodontal treatment in the past six months or antibiotics in the previous three months, undergoing systemic anti-inflammatory treatment,
* Pregnancy or lactation
* Serious illnesses, congenital adrenal hyperplasia, virilizing tumors, hypothyroidism, Cushing's syndrome, prolactinomas, cardiovascular diseases, or diabetes mellitus.
* Alcohol or drug abuse
* Psychiatric disorders.