Improving Endometrial Cancer Assessment by Combining Genomic Profiling and Surgical Assessment

Plain-language summary

This study looks at combining genomic profiling with surgical assessment (hysterectomy together with lymph node and peritoneal staging) to improve the assessment of endometrial cancer. It enrolls women aged 18 and over with a first diagnosis of endometrial cancer. It is a study with no assigned phase and is currently recruiting participants.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Not Applicable

Status

Recruiting

Sponsor

University Hospital, Gasthuisberg

Intervention

total hysterectomy with bilateral salpingo-oophorectomy, lymph node staging and comprehensive peritoneal staging

Start date

1/16/2023

Estimated completion

11/1/2028

Countries

Belgium

Related genes

Locations

• Leuven, Belgium

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Voluntary written informed consent of the participant or their legally authorized representative has been obtained before any screening procedures
* Women ≥ 18 years
* First diagnosis of EC, all disease stages and all histo-types

Exclusion Criteria:

* Participant has a history of pelvic or para-aortic lymph node dissection or sampling, previous pelvic (and/or para-aortic) radiotherapy, previous neoadjuvant chemotherapy
* Any disorder, which in the Investigator's opinion might jeopardise the participant's safety or compliance with the protocol
* Any prior or concomitant treatment(s) that might jeopardise the participant's safety or that would compromise the integrity of the Study