Comparative Study Between Photodynamic Therapy with LED Associated with Probiotics in the Treatment of Halitosis

Plain-language summary

This study compares the use of LED-based photodynamic therapy together with probiotics in the treatment of halitosis (bad breath). People diagnosed with halitosis by gas chromatography can take part. It is being conducted in Phase 1 and is still enrolling participants.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Phase 1

Status

Recruiting

Sponsor

University of Nove de Julho

Intervention

Oral hygiene at home, aPDT, Probiotics

Start date

11/1/2024

Estimated completion

12/30/2025

Countries

Brazil

Related genes

Locations

• São Paulo, Brazil

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Diagnosis of halitosis showing sulfhydride (SH2) ≥ 112 ppb in gas chromatography.

Exclusion Criteria:

* Individuals with dentofacial anomalies (such as cleft lip, cleft palate and nasopalatine);
* Undergoing orthodontic and/or orthopedic treatment;
* Undergoing oncological treatment;
* With systemic alterations (gastrointestinal, renal, hepatic)
* Undergoing antibiotic treatment up to 1 month before the research;
* Pregnant women.