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This study looks at how a blueberry-rich diet, compared with a control diet, affects people living with colitis (Crohn's Disease or Ulcerative Colitis). Adults over 18 who have had mild-to-moderate colitis for at least 6 months can take part. It is a study with no applicable phase and is currently recruiting participants.
The summary above is a plain-language rendering of the official record. The original English title is shown for reference.
Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.
Inclusion Criteria: * age \> 18 years * diagnosis of Crohn's Disease (CD) or Ulcerative Colitis (UC) with mild to moderate colitis for at least 6 months (CD: Harvey-Bradshaw-Index Score 5-16; UC: Partial Mayo Score 2-6) * stable IBD-specific medication dosage for at least 3 months \[such as 5-aminosalicylates (5-ASA), thiopurines or biologicals (therapeutic antibodies such as infliximab, adalimumab, vedolizumab, etc.)\] * inpatient admission to the Department for Internal and Integrative Medicine at the Sozialstiftung Bamberg, Germany for regular treatment * clinical indication and performance of an initial colonoscopy with confocal laser endomicroscopy (CLE) * signed informed consent form Exclusion Criteria: * IBD without inflammation of the colon (e.g. Crohn's Disease without colitis) * active flare of IBD * CRP ≥ 100 mg/l * artificial bowel outlet in front of the colon (ileostomy) * high regular consumption of blueberries (≥ 300 g cultivated blueberries or ≥ 150 g wild blueberries per week) or administration of blueberry therapy in the last 3 months * participation in another therapeutic study within the last 30 days * Known intolerance to blueberries or their ingredients such as contained anthocyanins or fructose (e.g. fructose malabsorption) * presence of known serious infectious diseases e.g. of the liver such as HIV, hepatitis B and C infection