Yükleniyor... / Loading...
This is a pharmacogenomic study using whole genome sequencing to understand how medicines affect people individually. People aged 18 to 100 who take at least 5 prescription or over-the-counter medicines or supplements can take part. It is a study with no applicable phase and is currently recruiting participants.
The summary above is a plain-language rendering of the official record. The original English title is shown for reference.
Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.
Inclusion Criteria: * Individuals taking 5 or more medications, including over the counter drugs, supplements, natural products, cannabis produces, or other recreational drugs. * Ability to give and comprehend the consent process. * Consent to donate urine samples, genetic data through buccal swabs and blood samples, and undergo a comprehensive history and physical examination. * All genders * Age 18-100 Exclusion Criteria: * Subject has been diagnosed or is being treated for any cancer other than basal cell cancer in the last 5 years. Patients with metastatic melanoma in the last 5 years will be excluded. * Admitted to hospice. * Patient has ever been diagnosed with Hepatitis B or C. * Patient has ever been diagnosed with active liver disease, hepatomegaly, grossly abnormal liver function. Meld score \>10, ALT, or AST \>100U/L or an AST/ALT ratio \>2 * Patients taking imidazole antifungal medication. * Declines to participate or interact with staff/share their medical status. * A diagnosis of Alzheimer's disease or related dementias in a medical record indicates a progressive, debilitating condition that impairs memory, thought processes, and functioning. * Pregnant patients will be excluded. * Individuals who are unable or unwilling to provide consent will be excluded. * Unable to verbally communicate and comprehend English language.