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Long-term Follow-up Study of Gene Therapy for Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic Variant

Plain-language summary

This study aims to provide long-term follow-up for participants who received the LX2020 gene therapy for arrhythmogenic cardiomyopathy (a disease of the heart muscle) caused by a disease-causing variant in the PKP2 (plakophilin-2) gene. It can include people who previously received this gene therapy in the LX2020-01 study. This is a non-phase study and is enrolling participants by invitation.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase
N/A
Status
Enrolling by invitation
Sponsor
Lexeo Therapeutics
Start date
8/29/2025
Estimated completion
8/1/2030
Countries
United States

Related genes

Locations

  • Ann Arbor, United States

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Participants who received LX2020 in study LX2020-01

Exclusion Criteria:

* Concurrent enrollment in any other clinical investigation involving use of an investigational agent.
This is not medical advice. Consult your specialist.
View the official record on ClinicalTrials.gov →