Fertility And Sexual Function In CAH: CALLIOPE

Plain-language summary

This study investigates fertility and sexual function in adults with congenital adrenal hyperplasia (CAH). It is open to men aged 18-65 and pre-menopausal women aged 18-55 who have a CAH diagnosis. It is a study without an assigned phase and is currently recruiting participants.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Recruiting

Sponsor

University of Roma La Sapienza

Start date

11/1/2024

Estimated completion

11/1/2030

Countries

Italy

Related genes

Locations

• Rome, Italy

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Adult patients, males in the age range 18-65 years and pre-menopausal females in the age range 18-55 years;
* a known/new diagnosis of CAH.

Exclusion Criteria:

* BMI \> 40 Kg/m2;
* Any other concomitant condition requiring steroid treatment;
* Severe liver and/or kidney disease;
* Thyroid dysfunctions (overt hyperthyroidism and hypothyroidism);
* Malignant neoplasms;
* Drug and alcohol abuse;
* Use of drugs acting on hormonal levels (e.g. antiandrogens);
* Psychiatric diseases;
* Postmenopausal women;
* Women taking combined oral contraceptive pill (women) or other contraceptives will require stability for at least 6 months.