Batı Afrikalılarda Tip 2 Diyabetin Genetiği

Sade dilde özet

Bu çalışma, Batı Afrikalılarda Tip 2 Diyabetin (Type 2 Diabetes) genetik nedenlerini araştırıyor. 25 yaşından büyük, Tip 2 diyabeti olan veya olmayan kişiler dahil edilmiştir. Faz uygulanmayan gözlemsel bir çalışmadır ve tamamlanmıştır.

Yukarıdaki özet, resmî kaydın sade dile aktarılmış halidir. Orijinal İngilizce başlık referans için gösterilir.

Deney bilgileri

Faz

N/A

Durum

Tamamlandı

Sponsor

National Human Genome Research Institute (NHGRI)

Başlangıç

03.02.2009

Ülkeler

Ghana, Nigeria

İlgili genler

Merkezler

• Accra, Ghana
• Kumasi, Ghana
• Enugu, Nigeria
• Ibadan, Nigeria
• Lagos, Nigeria

Uygunluk kriterleri

Kriterler ClinicalTrials.gov kaydından orijinal İngilizce haliyle alınmıştır. Uygunluk kararını yalnızca deneyi yürüten ekip verebilir.

* INCLUSION CRITERIA:

As our primary interest is in T2D, it is important to exclude individuals who may have diabetes of another etiology. Elevated blood glucose in individuals 25 years old or younger is unlikely (in West Africa) to result from T2D and may reflect Type 1 Diabetes. Therefore, only individuals older than 25 years will be included in this study.

We are seeking to enroll persons without T2D or with previously or newly diagnosed T2D. Previously diagnosed cases will be determined by self-report of being treated with oral medication or insulin. Newly diagnosed cases will be determined by fasting blood glucose value \>= 126 mg/dl on more than one occasion. Individuals who have elevated blood glucose during their initial reading will be asked to return to the study site for a second test. If this test also has a fasting blood glucose value \>= 126 mg/dl, then they will be considered a new case. The control group will be individuals with no report of T2D diagnosis and fasting plasma glucose (FPG)\< 126 mg/dl.

Only unrelated individuals will be included in this phase of the study to avoid confounding genetic association studies by relatedness in the study population.

EXCLUSION CRITERIA:

An individual who meets any of the following criteria will be excluded from participation in this study:

* Incarceration.
* Lack capacity to consent to research participation.
* Pregnancy.