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Metabolic and Epigenetic Impact of FAAH Inhibitors and OEA
Bu çalışma, OEA adlı bir takviyenin metabolik ve epigenetik etkilerini inceliyor. Çalışmaya, vücut kitle indeksi 25-30 arasında olan, metabolik hastalığı bulunmayan 18-64 yaş arası sağlıklı yetişkinler katılabiliyordu. Çalışma Faz uygulanmayan bir çalışma olarak yürütülmüş ve tamamlanmıştır.
Yukarıdaki özet, resmî kaydın sade dile aktarılmış halidir. Orijinal İngilizce başlık referans için gösterilir.
Kriterler ClinicalTrials.gov kaydından orijinal İngilizce haliyle alınmıştır. Uygunluk kararını yalnızca deneyi yürüten ekip verebilir.
Inclusion Criteria: * Adults ages 18-64 years old * BMI 25-30 inclusive (self-reported for screening, confirmed at first study visit) * For purposes of blood collection and other in-person procedures: o Reside within driving distance of the study center or be willing to travel to the study center * Willing and able to undergo three blood draws over 12 weeks * Willing to wash out of all internally-consumed essential oils or botanical products for at least 2 weeks prior to starting the study, and willing to maintain the washout for the duration of the study (14 weeks). * Willing and able to consume study product twice daily for about 12 weeks * Willing to track consumption of study product * Willing to keep diet, exercise, sleep habits, and current non-study supplement use the same throughout the study * Willing to limit alcohol consumption to "social drinking" (typically no more than 3 drinks per day and 7 per week) during the study * History of alcohol consumption limited to "social drinking" (typically no more than 3 drinks per day and 7 per week) * Willing to avoid recreational drugs and smoking/vaping for the duration of the study (approximately 12 weeks) * No metabolic disease (BMI\>30, diagnosis and treatment of hypertension, diabetes, or dyslipidemia) * No major diseases under treatment by doctor (Medical Reviewer's discretion) * No pregnancy within the last 60 days or currently breastfeeding (females) * No allergy to olive oil, lavender essential oil, ginger oleoresin/extract/essential oil, or OEA. * No regular internal consumption of lavender essential oil, ginger oleoresin or extract, or OEA within the last 1 month (regularly is defined as dosing daily for more than 2 consecutive weeks, or dosing more than 2-3 times per week for 4 consecutive weeks) * No evidence of medical condition, significant disease or disorder, medication, or surgery within the past 12 months that may, in the judgment of the medical provider, put the participant at risk or affect study results, procedures, or outcomes * No recreational drug or smoking/vaping use in the past 1 month * Not currently or previously participating in any other clinical trial within the last 30 calendar days Exclusion Criteria: * Failure to meet all inclusion criteria