Analysis of NF2 Mutations in Radiation-Related Neural Tumors

Plain-language summary

This study examines NF2 gene mutations in nerve tumors that develop in people who received radiation therapy to the head and neck during childhood. It included a group of patients who had received head-and-neck radiation for benign conditions before the age of 16. Sponsored by the National Cancer Institute (NCI), this observational study had no assigned phase and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Completed

Sponsor

National Cancer Institute (NCI)

Start date

8/1/1996

Estimated completion

7/1/2006

Countries

United States

Related genes

Locations

• Bethesda, United States

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

* INCLUSION CRITERIA:

Members of a cohort of 4,296 patients who received conventional (200 kV) radiation treatment to the head and neck for benign conditions before their 16th birthday.

All of the patients were treated at Michael Reese Hospital, Chicago, between 1939 and 1962.