A Qualitative Exploration of the Impact of Positive BRCA1/2 Mutation Status on the Lives of Young Women

Plain-language summary

This study qualitatively explores how a positive BRCA1 or BRCA2 gene mutation result affects the lives (such as relationships and family planning) of young women. It included women aged 18-35 who had BRCA1/2 testing and received a positive result. It is an observational (non-phase) study and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Completed

Sponsor

National Cancer Institute (NCI)

Start date

6/21/2011

Estimated completion

4/3/2015

Countries

United States

Related genes

Locations

• Bethesda, United States

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

* INCLUSION CRITERIA:
* Participants must be biologically female
* Participants must have reached their 18th birthday but not have passed their 35th birthday
* Participants must be able to speak and understand English with a level of fluency sufficient for completion of the recorded telephone interview
* Participants must have completed genetic testing for BRCA1/2 and received a positive test result (i.e., a deleterious or disease-related mutation was identified).
* Participants must have experienced or be contemplating/planning couple relationship(s), formation of a family, and/or utilization of risk management/reduction strategies at some point.

EXCLUSION CRITERIA:

-Potential participants will be excluded from the study if they do not agree to have their interview or focus group contributions audio recorded.